{"id":37,"date":"2021-10-12T19:18:22","date_gmt":"2021-10-12T10:18:22","guid":{"rendered":"http:\/\/antiage.sci.yokohama-cu.ac.jp\/?page_id=37"},"modified":"2026-04-23T15:58:41","modified_gmt":"2026-04-23T06:58:41","slug":"research","status":"publish","type":"page","link":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/research\/","title":{"rendered":"\u7814\u7a76\u5185\u5bb9"},"content":{"rendered":"\n

\uff11\uff0e\u7d30\u80de\u8001\u5316\u306e\u5206\u5b50\u6a5f\u69cb\u306e\u89e3\u6790<\/p>\n\n\n\n

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\u3000\u7d30\u80de\u8001\u5316\u306f\u3001\u52d5\u7269\u7d44\u7e54\u3092\u69cb\u6210\u3059\u308b\u4f53\u7d30\u80de\u304c\u7a2e\u3005\u306e\u30b9\u30c8\u30ec\u30b9\u306b\u66dd\u3055\u308c\u305f\u969b\u306b\u3001\u5206\u88c2\u80fd\u529b\u3092\u4e0d\u53ef\u9006\u7684\u306b\u55aa\u5931\u3059\u308b\u73fe\u8c61\u3067\u3042\u308b\u3002\u8001\u5316\u7d30\u80de\u306f\u5897\u6b96\u523a\u6fc0\u306b\u5fdc\u7b54\u305b\u305a\u7d30\u80de\u5206\u88c2\u306f\u3057\u306a\u3044\u304c\u3001\u4ee3\u8b1d\u6d3b\u52d5\u3092\u884c\u3044\u3001\u9577\u671f\u9593\u306b\u6e21\u308a\u751f\u5b58\u3067\u304d\u308b\u3002\u7d30\u80de\u8001\u5316\u306f\u3001\u7d30\u80de\u306e\u7570\u5e38\u5897\u6b96\u3092\u9632\u3050\u3053\u3068\u3067\u3001\u77ed\u671f\u7684\u306b\u306f\u304c\u3093\u5316\u6291\u5236\u6a5f\u69cb\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u3002\u4e00\u65b9\u3001\u8001\u5316\u7d30\u80de\u306f\u7279\u5fb4\u7684\u306a\u907a\u4f1d\u5b50\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u306e\u5909\u5316\u3092\u793a\u3057\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7b49\u306e\u5206\u6ccc\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u9ad8\u767a\u73fe\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u308b\u3002\u3053\u306e\u73fe\u8c61\u306fSenescence-Associated-Secretory-Phenotype (SASP)\u3068\u547c\u3070\u308c\u3001\u304c\u3093\u3084\u52a0\u9f62\u6027\u75be\u60a3\u306e\u767a\u75c7\u30fb\u9032\u884c\u306b\u5bc4\u4e0e\u3059\u308b\u3002\u52a0\u9f62\u306b\u4f34\u3044\u3001\u751f\u4f53\u5185\u306b\u8001\u5316\u7d30\u80de\u306f\u84c4\u7a4d\u3057\u3001\u8001\u5316\u7d30\u80de\u3092\u9664\u53bb\u3059\u308b\u3068\u3001\u8001\u5316\u3067\u898b\u3089\u308c\u308b\u69d8\u3005\u306a\u8868\u73fe\u578b\uff08\u8a8d\u77e5\u75c7\u3001\u7b4b\u8089\u306e\u8870\u3048\u3001\u5404\u7a2e\u81d3\u5668\u306e\u6a5f\u80fd\u4f4e\u4e0b\uff09\u304c\u6539\u5584\u3055\u308c\u308b\u3002\u307e\u305f\u3001SASP\u56e0\u5b50\u306b\u306f\u3001\u30ac\u30f3\u306e\u751f\u5b58\u3084\u5897\u6b96\u3092\u4fc3\u9032\u3059\u308b\u3082\u306e\u3082\u542b\u307e\u308c\u3001\u304c\u3093\u6cbb\u7642\u306b\u304a\u3044\u3066\u8001\u5316\u7d30\u80de\u306b\u3088\u308b\u30ac\u30f3\u5fae\u5c0f\u74b0\u5883\u306e\u5f62\u6210\u304c\u554f\u984c\u8996\u3055\u308c\u3066\u3044\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u6297\u8001\u5316\u304a\u3088\u3073\u304c\u3093\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u7d30\u80de\u8001\u5316\u306e\u5236\u5fa1\u304c\u65b0\u305f\u306a\u6a19\u7684\u306b\u306a\u308a\u3064\u3064\u3042\u308b\u3002 <\/p>\n<\/div>\n\n\n\n

\n
\"\"
\u56f3\uff11. \u7d30\u80de\u8001\u5316\u306e\u4e0d\u5747\u8861\u5897\u6b96\u7406\u8ad6<\/strong> \u3000<\/span>
\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u6b63\u5e38\u30fb\u4e0d\u6b7b\u5316\u30fb\u304c\u3093\u5316\u306b\u95a2\u4fc2\u306a\u304f\u3001\u4efb\u610f\u306e\u7d30\u80de\u306b\u304a\u3044\u3066\u7d30\u80de\u8001\u5316\u3092\u8a98\u5c0e\u3067\u304d\u308b\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u304d\u305f\u3002\u7d30\u80de\u7cfb\u306b\u3088\u3063\u3066\u8001\u5316\u5f62\u8cea\u306f\u591a\u69d8\u3067\u3042\u308b\u304c\u3001DNA\u8907\u88fd\u306e\u9045\u6ede\u3068\u7d30\u80de\u81a8\u5f35\u306f\u5171\u901a\u3057\u3066\u89b3\u5bdf\u3055\u308c\u308b\u3002\u3053\u308c\u3089\u306e\u7279\u5fb4\u304b\u3089\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u300c\u7d30\u80de\u8001\u5316\u306e\u4e0d\u5747\u8861\u5897\u6b96\u30e2\u30c7\u30eb\u300d\u3092\u63d0\u5531\u3057\u3066\u3044\u308b\u3002\u305d\u308c\u306f\u3001\u7d30\u80de\u969c\u5bb3\u306b\u3088\u308bDNA\u8907\u88fd\u306e\u9045\u6ede\u304c\u7d30\u80de\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u306a\u84c4\u7a4d\u3092\u3082\u305f\u3089\u3057\u3001\u7d30\u80de\u81a8\u5f35\u3068\u6838\u81a8\u5f35\u3092\u7d4c\u3066\u3001\u6838\u819c\u3068\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u8907\u5408\u4f53\u304c\u5d29\u58ca\u3059\u308b\u3068\u3044\u3046\u7d30\u80de\u8001\u5316\u306e\u666e\u904d\u7684\u306a\u30e2\u30c7\u30eb\u3067\u3042\u308b\u3002<\/figcaption><\/figure><\/div><\/div>\n<\/div>\n\n\n\n
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\u73fe\u5728\u3001\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u7d30\u80de\u8001\u5316\u306e\u5206\u5b50\u6a5f\u69cb\u3092\u89e3\u660e\u3059\u308b\u4e0a\u3067\u3001
\u2460\u7d30\u80de\u8001\u5316\u306b\u304a\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u306a\u84c4\u7a4d\u306e\u5f79\u5272<\/strong>
\u2461\u7d30\u80de\u8001\u5316\u306b\u304a\u3051\u308b\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u306e\u5f79\u5272 <\/strong>\u306b\u7740\u76ee\u3057\u3001\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u308b\u3002 <\/p>\n<\/div>\n\n\n\n

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\u2460\u7d30\u80de\u8001\u5316\u306b\u304a\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u306a\u84c4\u7a4d\u306e\u5f79\u5272<\/strong><\/p>\n\n\n\n

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\n

\u3000\u7814\u7a76\u5ba4\u3067\u306f\u3001\u7d30\u80de\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u306e\u5236\u9650\uff08\u6b63\u5e38\u306a\u5897\u6b96\u306b\u306f\u5f71\u97ff\u3057\u306a\u3044\uff09\u304c\u4e0d\u5747\u8861\u5897\u6b96\u3092\u89e3\u6d88\u3057\u3001\u7d30\u80de\u8001\u5316\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u305f\u3002\u307e\u305f\u3001\u3053\u306e\u5236\u9650\u306f\u3001\u6b63\u5e38\u7d30\u80de\u306e\u5206\u88c2\u5bff\u547d\u3092\u9855\u8457\u306b\u5ef6\u9577\u3057\u305f\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u5206\u88c2\u3092\u505c\u6b62\u3057\u305f\u8001\u5316\u7d30\u80de\u306e\u5897\u6b96\u3092\u518d\u958b\u3055\u305b\u305f\u3002\u500b\u4f53\u30ec\u30d9\u30eb\u306b\u304a\u3044\u3066\u3082\u30e2\u30c7\u30eb\u751f\u7269\u3067\u3042\u308b\u7dda\u866b\uff08C. elegans\uff09\u306e\u5e73\u5747\u5bff\u547d\u304a\u3088\u3073\u6700\u5927\u5bff\u547d\u3092\u5ef6\u9577\u3055\u305b\u305f\u3002

\u3000\u4eca\u5f8c\u306e\u8ab2\u984c\u306f\u3001\u7d30\u80de\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u306e\u5236\u9650\u306b\u3088\u308a\u3001\u30d2\u30c8\u306a\u3069\u306e\u9ad8\u7b49\u52d5\u7269\u306e\u8001\u5316\u9632\u6b62\u3092\u5b9f\u73fe\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3067\u3042\u308b\u3002\u305d\u306e\u305f\u3081\u306b\u306f\u3001\u7d30\u80de\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u305f\u8001\u5316\u6291\u5236\u5264\u306e\u63a2\u7d22\u3084\u958b\u767a\u3092\u9032\u3081\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002\u307e\u305f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6442\u53d6\u5236\u9650\u306a\u3069\u306e\u6804\u990a\u5b66\u7684\u898b\u5730\u304b\u3089\u3082\u8001\u5316\u9632\u6b62\u306e\u53ef\u80fd\u6027\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u3082\u91cd\u8981\u306b\u306a\u308b\u3002 <\/p>\n<\/div>\n\n\n\n

\n
\"\"
\u56f3\uff12.\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u5236\u9650\u306b\u3088\u308b\u7d30\u80de\u8001\u5316\u306e\u6291\u5236<\/strong>
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\u53f3\u56f3\uff1a\u30d2\u30c8\u6b63\u5e38\u7dda\u7dad\u82bd\u7d30\u80de\uff08TIG)\u306f\u57f9\u990a\u3092\u7d9a\u3051\u308b\u3068\u8001\u5316\u3059\u308b\uff08\u7d99\u4ee3\u8001\u5316\uff09\u3002\u30b7\u30af\u30ed\u3078\u30ad\u30b7\u30df\u30c9\uff08CHX\uff09\u3092\u3054\u304f\u5fae\u91cf\u6295\u4e0e\u3059\u308b\u3068\u3001\u5206\u88c2\u5bff\u547d\u3092\u9855\u8457\u306b\u5ef6\u9577\u3057\u305f\u3060\u3051\u3067\u306a\u304f\u3001\u5206\u88c2\u3092\u5b8c\u5168\u306b\u505c\u6b62\u3057\u305f\u8001\u5316\u7d30\u80de\u306e\u5897\u6b96\u304c\u518d\u958b\u3057\u305f\u3002\u9752\u3044\u7d30\u80de\u306f\u8001\u5316\u30de\u30fc\u30ab\u30fc\u304c\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\uff08Takauji\u00a0et al., Sci. Rep. 2016<\/a>\uff09\u3002<\/figcaption><\/figure><\/div>\n\n\n

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\u2461\u7d30\u80de\u8001\u5316\u306b\u304a\u3051\u308b\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u306e\u5f79\u5272<\/strong><\/p>\n\n\n\n

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\"\"
\u56f3\uff13. \u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u3068\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u76f8\u4e92\u4f5c\u7528 <\/strong> \u3000
\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u306e\u5927\u90e8\u5206\u306f\u3001\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u4ecb\u3057\u3066\u6838\u819c\u5185\u5074\u306b\u5c40\u5728\u3057\u3066\u3044\u308b\u3002\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u3092\u6838\u819c\u306b\u30a2\u30f3\u30ab\u30fc\u3059\u308b\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u591a\u6570\u77e5\u3089\u308c\u308b\u304c\u3001\u4e2d\u5fc3\u7684\u5f79\u5272\u3092\u679c\u305f\u3059\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306flamin A\/C\u3068lamin B receptor\uff08LBR\uff09\u3067\u3042\u308b\u3002\u4e21\u8005\u306e\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u306b\u3088\u308a\u6838\u819c\u8fd1\u508d\u306e\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u304c\u6d88\u5931\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\uff08Solovei et al. Cell. 2014)\u3002\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u306e\u5909\u5316\u306f\u3001\u5927\u898f\u6a21\u306a\u907a\u4f1d\u5b50\u767a\u73fe\u306e\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u4e88\u60f3\u3055\u308c\u308b\u304c\u3001\u305d\u308c\u306f\u8001\u5316\u7d30\u80de\u304c\u793a\u3059\u3001\u4e0d\u53ef\u9006\u7684\u306a\u5897\u6b96\u505c\u6b62\u3084SASP\u56e0\u5b50\u306e\u767a\u73fe\u306b\u5bc4\u4e0e\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002<\/figcaption><\/figure><\/div><\/div>\n\n\n\n
\n


\u3000\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u6b63\u5e38\u7d30\u80de\u3068\u304c\u3093\u7d30\u80de\u3092\u7528\u3044\u3066\u3001\u69d8\u3005\u306a\u65b9\u6cd5\u3067\u7d30\u80de\u8001\u5316\u3092\u8a98\u5c0e\u3057\u3001\u5171\u901a\u3057\u3066\u5909\u5316\u3092\u793a\u3059\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u63a2\u7d22\u3057\u3066\u304d\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u5f62\u6210\u306b\u91cd\u8981\u306a\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\uff08lamin A\/C, lamin B, LBR, LAP2\u03b2, Emerin, BAF, Nup153, Nup62, Nup214, Nup358\uff09\u306e\u3046\u3061\u3001\u7d30\u80de\u8001\u5316\u306b\u4f34\u3044\u3001\u5171\u901a\u3057\u3066\u6838\u819c\u3078\u306e\u5c40\u5728\u3092\u5931\u3063\u305f\u306e\u306fLBR\u3060\u3051\u3067\u3042\u3063\u305f\uff08Arai & En et al<\/em>., BBRC, 2016<\/a>\uff09\u3002\u307e\u305f\u3001LBR\u306f\u7d30\u80de\u8001\u5316\u306b\u4f34\u3044\u30bf\u30f3\u30d1\u30af\u8cea\u30ec\u30d9\u30eb\u3067\u6e1b\u5c11\u3059\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u305f\u3002
\u3000\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7570\u5e38\u306a\u84c4\u7a4d\u304c\u3001\u5c0f\u80de\u4f53\u30b9\u30c8\u30ec\u30b9\u304a\u3088\u3073\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u3088\u308b\u5206\u89e3\u7cfb\u3092\u4ecb\u3057\u3066LBR\u306e\u5c40\u5728\u5909\u5316\u30fb\u767a\u73fe\u4f4e\u4e0b\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u3092\u660e\u3089\u304b\u306b\u3057\u305f\uff08En et al<\/em>., FEBS Open Bio, 2020<\/a>\uff09\u3002\u3055\u3089\u306b\u3001LBR\u306e\u6a5f\u80fd\u4f4e\u4e0b\u304c\u7d30\u80de\u8001\u5316\u306b\u4f34\u3046\u5897\u6b96\u80fd\u306e\u55aa\u5931\u306b\u95a2\u4e0e\u3059\u308b\u3053\u3068\uff08Arai et al<\/em>., Mech Ageing Dev., 2019<\/a>\uff09\u3001LBR\u306fSASP\u907a\u4f1d\u5b50\u9818\u57df\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001SASP\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u5236\u5fa1\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u3053\u3068\u3092\u5831\u544a\u3057\u3066\u304d\u305f\uff08En et al<\/em>., Exp Cell Res., 2020<\/a>\uff09\u3002\u30bf\u30f3\u30d1\u30af\u8cea\u5408\u6210\u306e\u8abf\u7bc0\u3068\u540c\u69d8\u306b\u3001LBR\u306e\u6a5f\u80fd\u8abf\u7bc0\u306f\u7d30\u80de\u8001\u5316\u306e\u5236\u5fa1\u306b\u6709\u52b9\u306a\u624b\u6bb5\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u308b\u3002 <\/p>\n<\/div>\n<\/div>\n\n\n

\n
\"\"
\u56f3\uff14. \u300c\u7d30\u80de\u8001\u5316\u306e\u4e0d\u5747\u8861\u5897\u6b96\u7406\u8ad6\u300d\u306e\u5206\u5b50\u6a5f\u69cb
<\/strong>DNA\u8907\u88fd\u306e\u9045\u6ede\u306b\u4f34\u3046\u7d30\u80de\u8cea\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u84c4\u7a4d\u304c\u3001\u5c0f\u80de\u4f53\u306b\u304a\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u54c1\u8cea\u7ba1\u7406\u306b\u8ca0\u8377\u3092\u304b\u3051\u308b\u3002\u5c0f\u80de\u4f53\u306f\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5408\u6210\u5834\u6240\u3067\u3042\u308b\u3002\u305d\u306e\u305f\u3081\u3001\u5c0f\u80de\u4f53\u30b9\u30c8\u30ec\u30b9\u304c\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u5f62\u6210\u306b\u91cd\u8981\u306a\u6838\u819c\u30bf\u30f3\u30d1\u30af\u8ceaLBR\u306e\u7570\u5e38\u306b\u7e4b\u304c\u308b\u3002LBR\u304c\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u30d8\u30c6\u30ed\u30af\u30ed\u30de\u30c1\u30f3\u306b\u306f\u3001\u7d30\u80de\u8001\u5316\u95a2\u9023\u907a\u4f1d\u5b50\u304c\u542b\u307e\u308c\u3001\u7d30\u80de\u8001\u5316\u3092\u8a98\u5c0e\u3059\u308b\u3002<\/figcaption><\/figure><\/div>\n\n\n

<\/p>\n\n\n\n

\u3000<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

\uff11\uff0e\u7d30\u80de\u8001\u5316\u306e\u5206\u5b50\u6a5f\u69cb\u306e\u89e3\u6790 \u3000\u7d30\u80de\u8001\u5316\u306f\u3001\u52d5\u7269\u7d44\u7e54\u3092\u69cb\u6210\u3059\u308b\u4f53\u7d30\u80de\u304c\u7a2e\u3005\u306e\u30b9\u30c8\u30ec\u30b9\u306b\u66dd\u3055\u308c\u305f\u969b\u306b\u3001\u5206\u88c2\u80fd\u529b\u3092 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-37","page","type-page","status-publish","hentry","post"],"_links":{"self":[{"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/pages\/37","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/comments?post=37"}],"version-history":[{"count":25,"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/pages\/37\/revisions"}],"predecessor-version":[{"id":429,"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/pages\/37\/revisions\/429"}],"wp:attachment":[{"href":"https:\/\/antiage.sci.yokohama-cu.ac.jp\/index.php\/wp-json\/wp\/v2\/media?parent=37"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}